Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL6880967

Cc1ccc(S(=O)(=O)Oc2cccc3oc(=O)ccc23)cc1.S

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.55
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
ESR1 P03372 1/20 0.54
GAA P10253 1/20 0.54
ESR2 Q92731 1/20 0.54
CYP3A4 P08684 2/20 0.45
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
KCNA3 P22001 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA9 Q16790 1/20 0.43
VDR P11473 1/20 0.43
ALPL P05186 3/20 0.42
HTR6 P50406 1/20 0.42
MAOB P27338 2/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3918843 0.83 MEN1 (0.49) MEN1KMT2AESR1GAAESR2
SCHEMBL11001743 0.78 MAOA (0.58) MEN1KMT2AESR1GAAESR2
Hydrogen Sulfide SCHEMBL6877387 0.76 CA12 (0.54) MEN1KMT2AGAACA12CA1
SCHEMBL5671449 0.76 MAOB (0.45) MEN1KMT2AESR1GAAESR2
SCHEMBL3517598 0.74 CYP2A6 (0.40) CYP2A6GAAKCNA3CA12CA1
Hydrogen Sulfide SCHEMBL6881209 0.74 CYP2A6 (0.55) CYP2A6CYP3A4LMNAKCNA3CA12
SCHEMBL27738814 0.74 EPHX2 (0.58) MEN1KMT2AESR1GAAESR2
SCHEMBL5670908 0.73 MAOB (0.58) GAACYP3A4CA12CA1CA9
SCHEMBL1073454 0.73 MEN1 (0.68) MEN1KMT2AESR1GAAESR2
SCHEMBL8464810 0.72 CYP2A6 (0.56) CYP2A6CYP3A4LMNAKCNA3CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed