Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 10/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877392 | 1.00 | L3MBTL1 (0.41) | L3MBTL1MCHR1ADRA2ANLRP3HRH1 | |
| SCHEMBL6875937 | 0.94 | NLRP3 (0.47) | L3MBTL1MCHR1ADRA2ANLRP3 | |
| SCHEMBL6875941 | 0.94 | NLRP3 (0.47) | L3MBTL1MCHR1ADRA2ANLRP3 | |
| SCHEMBL4035978 | 0.86 | MCHR1 (0.55) | MCHR1ADRA2AHRH1HTR2BHTR1A | |
| SCHEMBL4210512 | 0.86 | MCHR1 (0.55) | MCHR1ADRA2AHRH1HTR2BHTR1A | |
| SCHEMBL6875594 | 0.86 | CYP2C9 (0.40) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6875598 | 0.86 | CYP2C9 (0.40) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6875589 | 0.86 | CYP2C9 (0.40) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6875039 | 0.81 | EPHX1 (0.51) | MCHR1ADRA2AHRH1HTR2BHTR1A | |
| SCHEMBL6875033 | 0.81 | EPHX1 (0.51) | MCHR1ADRA2AHRH1HTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |