Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | CCNT2 | O60583 | 2/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877399 | 1.00 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RCCNT1CCNT2 | |
| SCHEMBL6879458 | 0.91 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RTUBB3ALDH1A1 | |
| SCHEMBL6879461 | 0.91 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RTUBB3ALDH1A1 | |
| SCHEMBL6866557 | 0.89 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RTUBB3ADRA1A | |
| SCHEMBL6465834 | 0.89 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RTUBB3ADRA1A | |
| SCHEMBL6456916 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RGAAADRA1A | |
| SCHEMBL6456909 | 0.86 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RGAAADRA1A | |
| SCHEMBL6877468 | 0.86 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RADRA1AHRH1 | |
| SCHEMBL6877474 | 0.86 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RADRA1AHRH1 | |
| SCHEMBL6878131 | 0.86 | MCHR1 (0.44) | MCHR1ADRA2ANPY5RGAAADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |