Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877520 | 1.00 | NOX1 (0.51) | NOX1MCHR1GBA1MEN1KMT2A | |
| SCHEMBL6877480 | 0.86 | NOX1 (0.48) | NOX1MCHR1GBA1MEN1KMT2A | |
| SCHEMBL6877475 | 0.86 | NOX1 (0.48) | NOX1MCHR1GBA1MEN1KMT2A | |
| SCHEMBL27632522 | 0.82 | MCHR1 (0.44) | NOX1MCHR1MEN1KMT2AADRA2A | |
| SCHEMBL27632525 | 0.82 | MCHR1 (0.44) | NOX1MCHR1MEN1KMT2AADRA2A | |
| SCHEMBL4262113 | 0.79 | NOX1 (0.51) | NOX1GBA1MEN1KMT2APABPC1 | |
| SCHEMBL4262116 | 0.79 | NOX1 (0.51) | NOX1GBA1MEN1KMT2APABPC1 | |
| SCHEMBL4028034 | 0.79 | MCHR1 (0.59) | MCHR1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4028042 | 0.79 | MCHR1 (0.59) | MCHR1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL6874808 | 0.78 | MCHR1 (0.51) | MCHR1MEN1KMT2AADRA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |