Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714544 | 0.85 | ALDH1A1 (0.40) | PTGS2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL9862848 | 0.74 | CYP1A2 (0.63) | PTGS2PTGS1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31491188 | 0.72 | CYP1A2 (0.60) | PTGS2PTGS1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL18045052 | 0.72 | CYP1A2 (0.68) | PTGS2PTGS1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11151194 | 0.72 | CYP1A2 (0.60) | PTGS2PTGS1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL2937510 | 0.72 | CYP1A2 (0.39) | PTGS2SMN1; SMN2KDM4EALDH1A1POLB | |
| SCHEMBL712397 | 0.71 | ACHE (0.39) | SMN1; SMN2KDM4EALDH1A1HTTNPC1 | |
| SCHEMBL1742859 | 0.70 | CYP1A2 (0.74) | PTGS2PTGS1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL29926517 | 0.70 | CYP1A2 (0.74) | PTGS2PTGS1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL27720551 | 0.69 | PTGS2 (0.49) | PTGS2PTGS1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825280-B1 | RIGIDITY, NONWARPING, NONBLEEDING, ANTISTATIC AGENTS, WEATHERPROOF, IMPACT STRENGTH; OXIDATION AND HEAT RESISTANCE | JAPAN POLYCHEM CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| EP-1002814-A1 | PROPYLENE BLOCK COPOLYMER AND PROPYLENE RESIN COMPOSITION | Japan Polychem Corporation (JP) | 2000-05-24 | — | — | EP | disclosed |