Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8193760 | 0.86 | KDM4E (0.60) | RORCLMNAALDH1A1KDM4E | |
| SCHEMBL4500240 | 0.86 | GPR119 (0.58) | RORCGPR119 | |
| SCHEMBL10067757 | 0.83 | RORC (0.48) | RORCGPR119USP2MEN1KMT2A | |
| SCHEMBL3122573 | 0.80 | LMNA (0.61) | LMNAALDH1A1KDM4EMAPK1HTT | |
| Hydrochloric Acid SCHEMBL27788243 | 0.79 | LMNA (0.59) | LMNAALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL2958737 | 0.76 | TDP1 (0.53) | LMNAALDH1A1KDM4EUSP2PKM | |
| SCHEMBL12408703 | 0.76 | GPR119 (0.52) | RORCGPR119 | |
| SCHEMBL16292725 | 0.76 | KDM4E (0.53) | RORCLMNAALDH1A1KDM4E | |
| SCHEMBL31402902 | 0.76 | GPR119 (0.52) | RORCGPR119 | |
| SCHEMBL16309080 | 0.76 | KDM4E (0.53) | RORCLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432417-A2 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER | Aventis Pharma S.A. (FR) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003028721-A2 | SUBSTITUTED BENZIMIDAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCER | AVENTIS PHARMA S.A. (FR) | 2003-04-10 | — | — | WO | disclosed |