Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 14/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6872814 | 0.76 | ADORA2B (0.63) | ADORA2BADORA2AADORA1 | |
| SCHEMBL5713537 | 0.71 | ADORA2B (0.44) | ADORA2BADORA2AADORA1CRHR1 | |
| SCHEMBL6878422 | 0.69 | ADORA2A (0.48) | ADORA2BADORA2AADORA1MAPT | |
| SCHEMBL5713556 | 0.68 | ADORA2B (0.65) | ADORA2BADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL6876107 | 0.67 | ADORA2B (0.61) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6876108 | 0.66 | ADORA2B (0.79) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6570942 | 0.66 | ADORA2A (0.46) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6873459 | 0.66 | ADORA2B (0.56) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6868235 | 0.65 | ADORA2B (0.56) | ADORA2BADORA2AADORA1 | |
| SCHEMBL31252170 | 0.65 | LMNA (0.47) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456188-A1 | 7-AMINO-BENZOTHIAZOLE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053946-A1 | 7-AMINO-BENZOTHIAZOLE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-07-03 | — | — | WO | disclosed |