Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878139 | 0.77 | PDE5A (0.47) | MEN1KMT2APDE5AKDM4EPDE1A | |
| SCHEMBL6879293 | 0.72 | GAA (0.49) | ALDH1A1TDP1CNR2HTTNPC1 | |
| SCHEMBL6876782 | 0.72 | PDE5A (0.42) | PDE5AKDM4EPDE1APDE1BPDE1C | |
| SCHEMBL1758817 | 0.70 | PDE5A (0.50) | MEN1KMT2APDE5AKDM4EPDE1A | |
| SCHEMBL6880848 | 0.70 | PDE5A (0.41) | PDE5AKDM4EPDE1APDE1BPDE1C | |
| SCHEMBL7488591 | 0.69 | KMT2A (0.53) | MEN1KMT2AALDH1A1ITGB1ITGA4 | |
| SCHEMBL1758662 | 0.68 | EPHX2 (0.49) | KMT2AALDH1A1TDP1CNR2HTT | |
| SCHEMBL6036808 | 0.66 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1ITGB1ITGA4 | |
| SCHEMBL8350301 | 0.66 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1ITGB1ITGA4 | |
| SCHEMBL7493963 | 0.66 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |