Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877689 | 0.78 | CNR2 (0.48) | GAAHTTCNR2ALDH1A1TDP1 | |
| SCHEMBL1759205 | 0.74 | CNR2 (0.62) | GAAHTTCNR2 | |
| SCHEMBL6879978 | 0.74 | CNR2 (0.45) | GAAHTTCNR2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6878139 | 0.73 | PDE5A (0.47) | — | |
| SCHEMBL6876782 | 0.72 | PDE5A (0.42) | — | |
| SCHEMBL6878366 | 0.72 | MEN1 (0.39) | GAAHTTCNR2ALDH1A1TDP1 | |
| SCHEMBL6880848 | 0.71 | PDE5A (0.41) | MAPK1 | |
| SCHEMBL4968797 | 0.69 | SMN1; SMN2 (0.65) | GAAHTTALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL1759195 | 0.68 | GAA (0.53) | GAAHTTCNR2ALDH1A1 | |
| SCHEMBL21044371 | 0.68 | CTPS1 (0.55) | ALDH1A1SMN1; SMN2TP53HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011058582-A1 | HISTONE DEACETYLASE INHIBITORS FOR THE TREATMENT OF FUNGAL INFECTIONS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2011-05-19 | — | — | WO | disclosed |