Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 18/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 13/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878454 | 1.00 | MCHR1 (0.53) | MCHR1ADRA2ANPY5RKDRTEK | |
| SCHEMBL6463609 | 0.88 | MCHR1 (0.42) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6463604 | 0.88 | MCHR1 (0.42) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6458568 | 0.86 | SMN1; SMN2 (0.43) | MCHR1ADRA2A | |
| SCHEMBL6460801 | 0.86 | SMN1; SMN2 (0.43) | MCHR1ADRA2A | |
| SCHEMBL5527044 | 0.86 | MCHR1 (0.72) | MCHR1ADRA2ANPY5R | |
| SCHEMBL5527048 | 0.86 | MCHR1 (0.72) | MCHR1ADRA2ANPY5R | |
| SCHEMBL6874252 | 0.85 | ALDH1A1 (0.52) | MCHR1ADRA2A | |
| SCHEMBL6872176 | 0.82 | LMNA (0.53) | MCHR1ADRA2A | |
| SCHEMBL6872189 | 0.82 | LMNA (0.53) | MCHR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |