Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878669 | 1.00 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL6868513 | 0.90 | NPSR1 (0.50) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL6868508 | 0.90 | NPSR1 (0.50) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL6878795 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL6878792 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL6878845 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL6878840 | 0.89 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL6875306 | 0.89 | EPHX1 (0.54) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL6456275 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1LMNAHTT | |
| SCHEMBL6456286 | 0.89 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |