Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878715 | 1.00 | GLA (0.48) | GLAMCHR1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6873669 | 0.89 | MCHR1 (0.42) | MCHR1KDM4ESMN1; SMN2LMNAADRA2A | |
| SCHEMBL6873662 | 0.89 | MCHR1 (0.42) | MCHR1KDM4ESMN1; SMN2LMNAADRA2A | |
| SCHEMBL6872148 | 0.88 | ALDH1A1 (0.55) | MCHR1KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6872143 | 0.88 | ALDH1A1 (0.55) | MCHR1KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6877014 | 0.88 | KDM4E (0.41) | GLAMCHR1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6877017 | 0.88 | KDM4E (0.41) | GLAMCHR1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6879529 | 0.86 | MCHR1 (0.43) | MCHR1KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6879533 | 0.86 | MCHR1 (0.43) | MCHR1KDM4ESMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6877624 | 0.86 | GAA (0.51) | MCHR1KDM4ESMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |