Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877017 | 1.00 | KDM4E (0.41) | KDM4ELMNASMN1; SMN2ALOX12MCHR1 | |
| SCHEMBL6872723 | 0.92 | ALOX12 (0.49) | KDM4ELMNASMN1; SMN2ALOX12MCHR1 | |
| SCHEMBL6872718 | 0.92 | ALOX12 (0.49) | KDM4ELMNASMN1; SMN2ALOX12MCHR1 | |
| SCHEMBL6458280 | 0.90 | EPHX1 (0.43) | KDM4ELMNASMN1; SMN2MCHR1ADRA2A | |
| SCHEMBL6458274 | 0.90 | EPHX1 (0.43) | KDM4ELMNASMN1; SMN2MCHR1ADRA2A | |
| SCHEMBL6879660 | 0.89 | MCHR1 (0.40) | KDM4ELMNASMN1; SMN2MCHR1ADRA2A | |
| SCHEMBL6879666 | 0.89 | MCHR1 (0.40) | KDM4ELMNASMN1; SMN2MCHR1ADRA2A | |
| SCHEMBL6878705 | 0.88 | GLA (0.48) | KDM4ELMNASMN1; SMN2ALOX12MCHR1 | |
| SCHEMBL6878715 | 0.88 | GLA (0.48) | KDM4ELMNASMN1; SMN2ALOX12MCHR1 | |
| SCHEMBL6878770 | 0.86 | ALDH1A1 (0.45) | KDM4ELMNASMN1; SMN2ALOX12MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |