Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27792837 | 0.79 | MAOA (0.56) | MAOAMAOBCYP19A1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL10537421 | 0.76 | CYP19A1 (0.62) | MAOAMAOBCYP19A1CYP11B1 | |
| SCHEMBL28263864 | 0.73 | CYP19A1 (0.68) | CYP19A1CCR1CCR2 | |
| SCHEMBL18015826 | 0.71 | MAOB (0.57) | MAOAMAOBALDH1A1KDM4ENPC1 | |
| SCHEMBL21480315 | 0.71 | MAOB (0.57) | MAOAMAOBNPC1RAB9AHTR2C | |
| SCHEMBL2208757 | 0.71 | HDAC6 (0.60) | MAOAMAOBALDH1A1KDM4ENPC1 | |
| SCHEMBL8893064 | 0.71 | MAOB (0.57) | MAOAMAOBALDH1A1ADRA2AKDM4E | |
| SCHEMBL21480331 | 0.71 | MAOB (0.57) | MAOAMAOBALDH1A1ADRA2AKDM4E | |
| SCHEMBL4901772 | 0.71 | MAOB (0.57) | MAOAMAOBALDH1A1ADRA2AKDM4E | |
| SCHEMBL7112750 | 0.70 | MAOA (0.46) | MAOAMAOBALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262471-B1 | COMPOSITION AND USES FOR INFLUENCING HAIR GROWTH | LUCOLAS M D LTD (GB) | 2015-10-28 | — | — | EP | disclosed |
| US-20040018991-A1 | Topical treatment for mastalgia | MDI ONCOLOGY, INC. | 2004-01-29 | — | — | US | disclosed |