Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015826 | 0.72 | MAOB (0.57) | MAOAMAOBHTR2CPTPRCPTPN1 | |
| SCHEMBL21480315 | 0.72 | MAOB (0.57) | MAOAMAOBHTR2CPTPRCPTPN1 | |
| SCHEMBL2208757 | 0.72 | HDAC6 (0.60) | MAOAMAOBHTR2CPTPRCPTPN1 | |
| SCHEMBL8893064 | 0.72 | MAOB (0.57) | MAOAMAOBHTR2CPTPRCPTPN1 | |
| SCHEMBL4901772 | 0.72 | MAOB (0.57) | MAOAMAOBHTR2CPTPRCPTPN1 | |
| SCHEMBL21480331 | 0.72 | MAOB (0.57) | MAOAMAOBHTR2CPTPRCPTPN1 | |
| SCHEMBL1111832 | 0.72 | MAPK1 (0.47) | MAOAMAOBHTR2CMAPK1RECQL | |
| SCHEMBL6878764 | 0.70 | MAOA (0.44) | MAOAMAOBHTR2CMAPK1RECQL | |
| SCHEMBL30307575 | 0.70 | MAOB (0.50) | MAOAMAOBHTR2CPTPRCPTPN1 | |
| Hydrochloric Acid SCHEMBL10537421 | 0.69 | CYP19A1 (0.62) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030139442-A1 | Vasoactive agents | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139442-A1 | Vasoactive agents | VIPR2, VIPR1, GPR4 | MAOA 1289/4885MAOB 1744/4885HTR2C 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.