Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830882 | 0.86 | NOS1 (0.53) | HPGDALDH1A1KDM4ECYP1A2HSD17B10 | |
| SCHEMBL14012773 | 0.80 | NOS1 (0.41) | TP53HPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17115680 | 0.78 | KDM4E (0.44) | HPGDALDH1A1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL2964327 | 0.77 | FFAR1 (0.46) | SMN1; SMN2TSHRL3MBTL1FFAR1NPC1 | |
| SCHEMBL5657197 | 0.76 | NOTUM (0.48) | TP53HPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL12585924 | 0.76 | NQO1 (0.46) | TP53HPGDALDH1A1CYP1A2TSHR | |
| SCHEMBL15709664 | 0.75 | NOS1 (0.44) | HPGDALDH1A1KDM4ESMN1; SMN2CYP1A2 | |
| SCHEMBL10743352 | 0.75 | NOS1 (0.48) | HPGDALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL31422511 | 0.75 | KDM4E (0.36) | MITFTP53NCOA3ALDH1A1KDM4E | |
| SCHEMBL7715426 | 0.74 | NOS2 (0.54) | KDM4ECYP1A2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490366-A1 | NOVEL ALKOXYPYRIDINE-DERIVATIVES | ALTANA Pharma AG (DE) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003080607-A1 | NOVEL ALKOXYPYRIDINE-DERIVATIVES | ALTANA PHARMA AG (DE) | 2003-10-02 | — | — | WO | disclosed |