Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881288 | 0.88 | NPSR1 (0.37) | NPSR1KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL8700619 | 0.73 | CA2 (0.33) | — | |
| SCHEMBL3235703 | 0.72 | NR1H4 (0.43) | GAA | |
| SCHEMBL2675286 | 0.72 | CA2 (0.34) | GAA | |
| SCHEMBL6155451 | 0.72 | NLRP3 (0.33) | — | |
| SCHEMBL4677041 | 0.72 | CA2 (0.38) | GAA | |
| SCHEMBL8606290 | 0.71 | MTNR1A (0.45) | NPSR1KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL8609305 | 0.69 | MTNR1A (0.43) | MTNR1AMTNR1B | |
| SCHEMBL6771911 | 0.69 | CA2 (0.34) | — | |
| SCHEMBL9371440 | 0.68 | CA2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |