Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879650 | 1.00 | MCHR1 (0.49) | MCHR1RAB9ARXFP1MAPTADRA2A | |
| SCHEMBL6877538 | 0.88 | MCHR1 (0.53) | MCHR1RAB9ARXFP1MAPTADRA2A | |
| SCHEMBL6877534 | 0.88 | MCHR1 (0.53) | MCHR1RAB9ARXFP1MAPTADRA2A | |
| SCHEMBL6879862 | 0.86 | MCHR1 (0.57) | MCHR1RAB9AADRA2AKDM4ESMN1; SMN2 | |
| SCHEMBL6879865 | 0.86 | MCHR1 (0.57) | MCHR1RAB9AADRA2AKDM4ESMN1; SMN2 | |
| SCHEMBL6456858 | 0.85 | KLK7 (0.62) | RAB9AKDM4EGLAPKMAPEX1 | |
| SCHEMBL6456853 | 0.85 | KLK7 (0.62) | RAB9AKDM4EGLAPKMAPEX1 | |
| SCHEMBL27651773 | 0.85 | MCHR1 (0.52) | MCHR1RAB9ARXFP1MAPTADRA2A | |
| SCHEMBL6878501 | 0.85 | RAB9A (0.56) | MCHR1RAB9ARXFP1MAPTADRA2A | |
| SCHEMBL6878491 | 0.85 | RAB9A (0.56) | MCHR1RAB9ARXFP1MAPTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |