Benzenesulfonamide

Benzenesulfonamide

SCHEMBL6879868

NS(=O)(=O)c1ccccc1.[NaH]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 18/20 0.94
CA1 P00915 16/20 0.94
CA12 O43570 15/20 0.94
CA9 Q16790 15/20 0.94
CA14 Q9ULX7 7/20 0.94
CA6 P23280 5/20 0.94
CA5A P35218 5/20 0.94
CA7 P43166 5/20 0.94
CA5B Q9Y2D0 5/20 0.94
CA4 P22748 4/20 0.94
CA3 P07451 4/20 0.94
CA13 Q8N1Q1 3/20 0.94
PLA2G7 Q13093 1/20 0.94
SOS1 Q07889 1/20 0.60
HTR6 P50406 1/20 0.55
USP2 O75604 1/20 0.55
TSHR P16473 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
AGO2 Q9UKV8 1/20 0.55
CYP2C19 P33261 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzenesulfonamide SCHEMBL27508711 1.00 CA2 (0.94) CA2CA1CA12CA9CA14
Benzenesulfonamide SCHEMBL729 0.97 CA2 (1.00) CA2CA1CA12CA9CA14
Benzenesulfonamide SCHEMBL28257999 0.97 CA2 (1.00) CA2CA1CA12CA9CA14
Benzenesulfonamide SCHEMBL6868390 0.97 CA2 (1.00) CA2CA1CA12CA9CA14
Benzenesulfonamide SCHEMBL1332409 0.97 CA2 (1.00) CA2CA1CA12CA9CA14
SCHEMBL19479299 0.97 CA2 (1.00) CA2CA1CA12CA9CA14
Benzenesulfonamide SCHEMBL29825137 0.97 CA2 (1.00) CA2CA1CA12CA9CA14
Benzenesulfonamide SCHEMBL861258 0.94 CA2 (0.94) CA2CA1CA12CA9CA14
Benzenesulfonamide SCHEMBL1009443 0.94 CA2 (0.94) CA2CA1CA12CA9CA14
Benzenesulfonamide SCHEMBL7517039 0.94 CA2 (0.94) CA2CA1CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115474609-A Disinfectant, preparation method thereof and film 苏州北辰新材料科技有限公司 2022-12-16 CN claimed
CN-109777648-A A kind of glassware special purpose detergent and preparation method thereof 吴苹 2019-05-21 CN claimed
CN-108929588-A Effectively remove the technology for realizing the product spray printing two dimensional code of information source tracing 安徽胜利精密制造科技有限公司 2018-12-04 CN claimed
CN-104450248-A Special detergent for glass products and preparation method of detergent ANHUI ZONGYI PACKAGING TECHNOLOGY CO LTD 2015-03-25 CN claimed
CN-1038313-A Cleaning agent for greasy dirt of mechanical parts YANG LIXUAN (CN) 1989-12-27 CN claimed
JP-62151757-A None JP disclosed
JP-55047652-A None JP disclosed
CN-115784944-A Synthesis method of high-purity environment-friendly acid dye intermediate 宿迁虹光化学工业有限公司 2023-03-14 CN disclosed
CN-115474609-A Disinfectant, preparation method thereof and film 苏州北辰新材料科技有限公司 2022-12-16 CN disclosed
CN-114727959-A Modification of plant messenger packages with charged lipids 旗舰创业创新六公司 2022-07-08 CN disclosed
CN-114245799-A Compositions and methods related to plant messenger packages 旗舰创业创新六公司 2022-03-25 CN disclosed
US-11186566-B2 Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator VERTEX PHARMACEUTICALS INCORPORATED (US) 2021-11-30 US disclosed
US-4242273-A ANTILIPEMIC AND ANTICHOLESTEROL AGENTS AMERICAN CYANAMID COMPANY (US) 1980-12-30 US disclosed
US-4230878-A AND 4-(UNSATURATED ALKYL)AMINOBENZOIC ACIDS AND DERIVATIVES AMERICAN CYANAMID COMPANY (US) 1980-10-28 US disclosed
US-4227014-A ANTILIPEMIC AGENTS, ANTIATHEROSCLEROTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1980-10-07 US disclosed
US-4211783-A Hypolipidemic and antiatherosclerotic novel 4-(aralkyl- and heteroarylalkylamino)phenyl compounds AMERICAN CYANAMID COMPANY (US) 1980-07-08 US disclosed
US-4205085-A Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino)phenyl compounds AMERICAN CYANAMID COMPANY (US) 1980-05-27 US disclosed
JP-S5547652-A PRODUCTION OF SUBSTITUTED SULFONDIIMINE WAKO PURE CHEM IND LTD 1980-04-04 JP disclosed
EP-0003663-A2 Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-08-22 EP disclosed
US-4136256-A HYPOLIPIDEMIC, ANTIATHEROSCLEROTIC AMERICAN CYANAMID COMPANY (US) 1979-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11186566-B2 Modulator of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator CFTR, SLC26A4, ABCB11 CA2 1660/4885CA1 4781/4885CA12 3219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.