Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 3/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908576 | 0.91 | HCRTR1 (0.44) | SRD5A1 | |
| SCHEMBL11379782 | 0.83 | HTR6 (0.39) | — | |
| SCHEMBL7280680 | 0.80 | LMNA (0.43) | — | |
| SCHEMBL7280684 | 0.80 | LMNA (0.43) | — | |
| SCHEMBL20760564 | 0.79 | DDB1 (0.39) | SRD5A1ABCB1DDB1CRBN | |
| SCHEMBL28194215 | 0.79 | DDB1 (0.39) | SRD5A1ABCB1DDB1CRBN | |
| SCHEMBL11380590 | 0.79 | KMT2A (0.47) | — | |
| SCHEMBL27483357 | 0.79 | CRBN (0.49) | CRBN | |
| SCHEMBL19411904 | 0.78 | HDAC6 (0.41) | DDB1CRBN | |
| SCHEMBL19411905 | 0.78 | HDAC6 (0.41) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011114103-A1 | PYRIMIDINONES FOR USE AS MEDICAMENTS | BIOLIPOX AB (SE) | 2011-09-22 | — | — | WO | disclosed |
| WO-2010029299-A1 | PYRIMIDINONE DERIVATIES FOR USE AS MEDICAMENTS | BIOLIPOX AB (SE) | 2010-03-18 | — | — | WO | disclosed |
| US-5006511-A | Treating hypertension, congestive heart failure | MERCK & CO., INC. (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0312283-A2 | Di-or tripeptide renin inhibitors containing lactam conformational restrictions in ACHPA | MERCK & CO. INC. (US) | 1989-04-19 | — | — | EP | disclosed |
| US-4279918-A | ANTIDEPRESSANTS, STIMULANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK G.M.B.H. (DE) | 1981-07-21 | — | — | US | disclosed |