Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880131 | 1.00 | ALDH1A1 (0.38) | ALDH1A1CYP3A4RECQLRARBKDM4E | |
| SCHEMBL6854034 | 0.81 | RARB (0.36) | ALDH1A1RARBKDM4ESMN1; SMN2HPGD | |
| SCHEMBL6850537 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP3A4RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL6876935 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP3A4RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL6876926 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP3A4RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL6850530 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CYP3A4RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL6228723 | 0.78 | ADRB2 (0.44) | ALDH1A1CYP3A4RECQLRAB9ANPC1 | |
| SCHEMBL6228721 | 0.78 | ADRB2 (0.44) | ALDH1A1CYP3A4RECQLRAB9ANPC1 | |
| SCHEMBL2837688 | 0.77 | ALOX5 (0.52) | ALDH1A1CYP3A4RECQLKDM4ESMN1; SMN2 | |
| SCHEMBL2837690 | 0.77 | ALOX5 (0.52) | ALDH1A1CYP3A4RECQLKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | Q6ZSR9, ACSL6, RPS4Y1 | ALDH1A1 2109/4885CYP3A4 1004/4885RECQL 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.