SCHEMBL6880170

SCHEMBL6880170

O=C(N=S(=O)=O)NCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
HTT P42858 1/20 0.54
GAA P10253 2/20 0.52
ALDH1A1 P00352 4/20 0.50
TSHR P16473 3/20 0.50
CYP2D6 P10635 2/20 0.50
CYP2C19 P33261 2/20 0.50
POLB P06746 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
EPHX1 P07099 1/20 0.49
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
ALOX12 P18054 2/20 0.48
HPGD P15428 1/20 0.48
HDAC2 Q92769 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27972375 0.78 ALDH1A1 (0.55) KMT2AMEN1GAAALDH1A1TSHR
SCHEMBL969256 0.78 ALDH1A1 (0.55) KMT2AMEN1GAAALDH1A1TSHR
Potassium Ion SCHEMBL1674285 0.77 GAA (0.52) KMT2AMEN1GAAALDH1A1TSHR
SCHEMBL7984182 0.77 GAA (0.52) KMT2AMEN1GAAALDH1A1TSHR
SCHEMBL4601814 0.77 KMT2A (0.42) KMT2AMEN1HTTGAAALDH1A1
SCHEMBL15038977 0.76 CYP2D6 (0.53) KMT2AMEN1GAAALDH1A1TSHR
SCHEMBL970224 0.76 RIPK1 (0.53) KMT2AMEN1GAAALDH1A1TSHR
SCHEMBL8000510 0.76 CYP2D6 (0.53) KMT2AMEN1GAAALDH1A1TSHR
SCHEMBL714625 0.74 EPHX1 (0.77) KMT2AMEN1GAAALDH1A1TSHR
SCHEMBL3056874 0.74 KMT2A (0.71) KMT2AMEN1HTTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1049656-A Replace N-(quinoline-2-base-methoxyl group) benzyl sulfonylurea BAYER AG (DE) 1991-03-06 CN claimed
CN-101674727-B Pyridonecarboxamides crop protection agents containing the same method for production and use thereof BAYER CROPSCIENCE AG 2014-06-25 CN disclosed
CN-1829442-B Safeners based on aromatic-aliphatic carboxylic acid derivatives BAYER CROPSCIENCE GMBH 2011-05-04 CN disclosed
CN-1829437-B Use of hydroxyaromatic compounds as safeners BAYER CROPSCIENCE GMBH 2011-03-30 CN disclosed
CN-1764374-B Use of aromatic hydroxy compounds as safeners BAYER CROPSCIENCE GMBH 2010-09-22 CN disclosed
CN-101785473-A Safening method BAYER CROPSCIENCE GMBH 2010-07-28 CN disclosed
CN-1949966-B Quinoxalin-2-one derivatives, crop protection agents comprising the same and method for production and use therof BAYER CROPSCIENCE GMBH 2010-05-26 CN disclosed
CN-101621924-A Oil suspension concentrate with micro-encapsulated agrochemical active ingredients BAYER CROPSCIENCE AG 2010-01-06 CN disclosed
CN-101583281-A Penetration enhancer for herbicides and safeners BAYER CROPSCIENCE AG (DE) 2009-11-18 CN disclosed
CN-101562968-A New microemulsion concentrates BAYER CROPSCIENCE AG (DE) 2009-10-21 CN disclosed
CN-1102142-C Novel N-acyl sulphonamides, novel mixtures of herbicides and antidotes and their use HOECHST SCHERING AGREVO GMBH (DE) 2003-02-26 CN disclosed
CN-1382016-A Anhydrous or low-water suspension concentrates of active substance mixtures for plant protection AVENTIS CROPSCIENCE GMBH (DE) 2002-11-27 CN disclosed
CN-1092189-C Substituted isoxazolines, process for producing them, agents containing them and their use as safeners HOECHEST SCHERING AGREVO GMBH (DE) 2002-10-09 CN disclosed
CN-1066133-C Substituted (hetero) aryl compounds, process for preparation, agents containing them, and their us safeners HOECHST AG (DE) 2001-05-23 CN disclosed
CN-1219840-A Novel N-acyl sulphonamides, novel mixtures of herbicides and antidotes and their use HOECHST SCHERING AGREVO GMBH (DE) 1999-06-16 CN disclosed
CN-1133038-A Substituted isoxazolines, process for producing them, agents containing them and their use as safeners HOECHST SCHERING AGREVO GMBH (DE) 1996-10-09 CN disclosed
CN-1086805-A (mixing) aryl compound that replaces, its preparation method, its preparation and purposes HOECHST AG (DE) 1994-05-18 CN disclosed
CN-1049656-A Replace N-(quinoline-2-base-methoxyl group) benzyl sulfonylurea BAYER AG (DE) 1991-03-06 CN disclosed
CN-1049656-A Replace N-(quinoline-2-base-methoxyl group) benzyl sulfonylurea BAYER AG (DE) 1991-03-06 CN disclosed
CN-1049656-A Replace N-(quinoline-2-base-methoxyl group) benzyl sulfonylurea BAYER AG (DE) 1991-03-06 CN disclosed