Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL969256 | 0.78 | ALDH1A1 (0.55) | GAAKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27972375 | 0.78 | ALDH1A1 (0.55) | GAAKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4588132 | 0.78 | GSK3B (0.41) | GAAKMT2AMEN1ALDH1A1LMNA | |
| Potassium Ion SCHEMBL1674285 | 0.77 | GAA (0.52) | GAAKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6880170 | 0.77 | KMT2A (0.54) | GAAKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3166632 | 0.77 | POLB (0.44) | KMT2ACYP2C9CYP2C19TSHRMEN1 | |
| SCHEMBL8000510 | 0.76 | CYP2D6 (0.53) | GAAKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL970224 | 0.76 | RIPK1 (0.53) | GAAKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL15038977 | 0.76 | CYP2D6 (0.53) | GAAKMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL714625 | 0.74 | EPHX1 (0.77) | GAAKMT2ACYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |