Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6876882 | 0.89 | MCHR1 (0.39) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL7046594 | 0.89 | ALDH1A1 (0.50) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6463063 | 0.88 | NPY5R (0.41) | MCHR1NPY5RALDH1A1CYP1A2MEN1 | |
| SCHEMBL6463065 | 0.88 | NPY5R (0.41) | MCHR1NPY5RALDH1A1CYP1A2MEN1 | |
| SCHEMBL7041689 | 0.86 | MCHR1 (0.43) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL3947714 | 0.85 | MCHR1 (0.58) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL3947716 | 0.85 | MCHR1 (0.58) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6463839 | 0.84 | MCHR1 (0.60) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6463836 | 0.84 | MCHR1 (0.60) | MCHR1ADRA2ANPY5RADRA1AHTR2B | |
| SCHEMBL6879328 | 0.84 | MCHR1 (0.52) | MCHR1ADRA2ANPY5RADRA1AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |