Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 10/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880422 | 0.89 | MCHR1 (0.43) | ALDH1A1GAAMCHR1ADRA2AHTR1A | |
| SCHEMBL6874339 | 0.88 | ADRA2A (0.44) | ALDH1A1GAATSHREPHX1MCHR1 | |
| SCHEMBL6460210 | 0.87 | EHMT2 (0.44) | TSHRMCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6460216 | 0.87 | EHMT2 (0.44) | TSHRMCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6876683 | 0.87 | ENPP2 (0.46) | ALDH1A1MCHR1ADRA2AMEN1KMT2A | |
| SCHEMBL6877138 | 0.86 | EPHX2 (0.48) | ALDH1A1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6877146 | 0.86 | EPHX2 (0.48) | ALDH1A1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL7043626 | 0.84 | MCHR1 (0.44) | EPHX1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6875033 | 0.84 | EPHX1 (0.51) | EPHX1MCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL6875039 | 0.84 | EPHX1 (0.51) | EPHX1MCHR1ADRA2AHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |