SCHEMBL6880679

SCHEMBL6880679

CC(Br)NC(=O)OCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.61
CTSK P43235 7/20 0.58
CTRB1 P17538 2/20 0.57
ELANE P08246 2/20 0.57
CTSS P25774 6/20 0.56
CTSL P07711 5/20 0.56
CTSB P07858 3/20 0.54
PRTN3 P24158 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11094221 0.88 ATM (0.62) ATMCTSKCTRB1ELANECTSS
SCHEMBL14704026 0.87 ATM (0.61) ATMCTSKCTRB1ELANECTSS
SCHEMBL6841166 0.87 ATM (0.61) ATMCTSKCTRB1ELANECTSS
SCHEMBL12942877 0.87 ATM (0.61) ATMCTSKCTRB1ELANECTSS
SCHEMBL8041576 0.86 ATM (0.64) ATMCTSKCTRB1ELANECTSS
SCHEMBL308291 0.86 ATM (0.64) ATMCTSKCTRB1ELANECTSS
SCHEMBL2059541 0.85 ATM (0.62) ATMCTSKCTRB1ELANECTSS
SCHEMBL22808751 0.85 ATM (0.62) ATMCTSKCTRB1ELANECTSS
SCHEMBL1891573 0.84 ALDH1A1 (0.56) ATMCTSKCTRB1ELANECTSS
SCHEMBL6358961 0.84 ATM (0.58) ATMCTSKCTRB1ELANECTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105601550-B Stimuli-sensitive multifunctional polyisocyanates having reactive groups 四川大学 2020-06-16 CN disclosed
CN-105601549-B Stimuli-sensitive diisocyanates 四川大学 2020-06-16 CN disclosed
US-6689616-B1 DETERMINING GLOMERULAR FILTRATION RATE IN HUMANS ROCHE DIAGNOSTICS GMBH (DE) 2004-02-10 US disclosed
EP-1040168-B1 NOVEL DYE-POLYSACCHARIDE-CONJUGATES AND THE UTILIZATION THEREOF AS A DIAGNOSTIC ROCHE DIAGNOSTICS GMBH (DE) 2002-11-06 EP disclosed
EP-1040168-A1 NOVEL DYE-POLYSACCHARIDE-CONJUGATES AND THE UTILIZATION THEREOF AS A DIAGNOSTIC Roche Diagnostics GmbH (DE) 2000-10-04 EP disclosed
WO-1999031183-A1 NOVEL DYE-POLYSACCHARIDE-CONJUGATES AND THE UTILIZATION THEREOF AS A DIAGNOSTIC ROCHE DIAGNOSTICS GMBH (DE) 1999-06-24 WO disclosed
US-5525474-A IMMUNOASSAY; LINKING THE HAPTENIC DRUG VIA ITS MALEIMIDE MOIETY AND A SULFHYDRYL BRIDGE TO AN IMMUNOGENIC CARRIER TO STIMULATE ANTIBODIES BOEHRINGER MANNHEIM CORPORATION (US) 1996-06-11 US disclosed
US-4804684-A ANTICONVULSANTS, ANALGESICS PANMEDICA S.A. (FR) 1989-02-14 US disclosed
EP-0236151-A1 Symmetrically O-disubstituted oximes of benzocondensed beta-diketocycloalkenes, processes for their preparation and their use as medicaments PANMEDICA S.A. (FR) 1987-09-09 EP disclosed