Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869683 | 0.92 | ALDH1A1 (0.41) | F10TPSAB1F2PRSS1PLG | |
| SCHEMBL9100846 | 0.91 | DDAH1 (0.44) | F10TPSAB1F2PRSS1PLG | |
| SCHEMBL9028427 | 0.82 | F10 (0.48) | F10TPSAB1F2PRSS1PLG | |
| SCHEMBL6879854 | 0.81 | MAPT (0.42) | ALDH1A1 | |
| SCHEMBL6879873 | 0.81 | MAPT (0.42) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11298541 | 0.80 | HDAC6 (0.44) | PRSS1PLAUALDH1A1 | |
| SCHEMBL549168 | 0.78 | HDAC6 (0.39) | F10F2PRSS1PLGPLAU | |
| SCHEMBL9110850 | 0.78 | F10 (0.45) | F10TPSAB1F2PRSS1PLG | |
| SCHEMBL9113789 | 0.77 | F10 (0.47) | F10TPSAB1F2PRSS1PLG | |
| SCHEMBL9027676 | 0.77 | KDM4E (0.44) | F10TPSAB1F2PRSS1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815461-B1 | ADMINISTERING BIS-BENZIMIDAZOLE COMPOUND; TREATING HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2004-11-09 | — | — | US | disclosed |