SCHEMBL68815

SCHEMBL68815

Oc1ccc(C2CCCCC2)cc1O

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
QDPR P09417 3/20 0.66
ACMSD Q8TDX5 2/20 0.62
HDAC4 P56524 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
KMO O15229 1/20 0.46
MEN1 O00255 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
PTPN1 P18031 1/20 0.46
ALOX5 P09917 1/20 0.46
BACE1 P56817 2/20 0.43
EPHX2 P34913 1/20 0.42
NUDT1 P36639 1/20 0.42
SERPINE1 P05121 1/20 0.42
HSP90AA1 P07900 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1291751 0.98 QDPR (0.68) QDPRACMSDHDAC4HDAC2HDAC8
SCHEMBL28188871 0.93 QDPR (0.68) QDPRACMSDHDAC4HDAC2HDAC8
SCHEMBL108606 0.89 QDPR (0.73) QDPRACMSDHDAC4HDAC2HDAC8
SCHEMBL10282755 0.89 QDPR (0.73) QDPRACMSDHDAC4HDAC2HDAC8
SCHEMBL15387357 0.86 QDPR (0.59) QDPRACMSDHDAC4HDAC2HDAC8
SCHEMBL7932026 0.85 ACMSD (0.61) QDPRACMSDHDAC4HDAC2HDAC8
SCHEMBL4960985 0.83 ACMSD (0.54) QDPRACMSDHDAC4HDAC2HDAC8
SCHEMBL19665789 0.83 ACMSD (0.59) QDPRACMSDHDAC4HDAC2HDAC8
SCHEMBL918287 0.83 ACMSD (0.59) QDPRACMSDHDAC4HDAC2HDAC8
SCHEMBL4958890 0.83 ACMSD (0.54) QDPRACMSDHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009017848-A9 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF AMYLOID DISEASES SUCH AS SYSTEMIC AA AMYLOIDOSIS PROTEO TECH INC (US) 2009-04-30 WO claimed
WO-2009017848-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF AMYLOID DISEASES SUCH AS SYSTEMIC AA AMYLOIDOSIS PROTEO TECH INC. (US) 2009-02-05 WO claimed
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
EP-1511710-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES SUCH AS ALZHEIMER S DISEASE, TYPE 2 DIABETES, AND PARKINSON S DISEASE Proteotech, Inc. (US) 2005-03-09 EP claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed
WO-2003101927-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF AMYLOID DISEASES AND SYNUCLEINOPATHIES SUCH AS ALZHEIMER'S DISEASE, TYPE 2 DIABETES, AND PARKINSON'S DISEASE PROTEOTECH, INC. (US) 2003-12-11 WO claimed
CN-109233371-B Nano self-cleaning coating liquid, self-cleaning product and preparation method thereof 深圳市天得一环境科技有限公司 2021-04-06 CN disclosed
EP-2318477-B1 ADDITIVES TO PREVENT DEGRADATION OF CYCLIC ALKENE DERIVATIVES FUJIFILM ELECTRONIC MAT USA INC (US) 2019-06-05 EP disclosed
EP-2851359-A1 METHOD FOR PRODUCING 4,4''-DIHYDROXY-M-TERPHENYLS Honshu Chemical Industry Co., Ltd. (JP) 2015-03-25 EP disclosed
US-8252704-B2 Additives to prevent degradation of cyclic alkene derivatives FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2012-08-28 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-4108850-A Positive-working immobile photographic azo compounds EASTMAN KODAK COMPANY (US) 1978-08-22 US disclosed
US-4069052-A Color photographic materials with spiro heterocyclic stabilizing agents comprising 2-imidazolidine-4',5'-dione rings AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1978-01-17 US disclosed
US-4061617-A ANTIOXIDANT, DIELECTRIC STABILIZERS, SEMICONDUCTORS, ION EXCHANGE RESINS GENERAL ELECTRIC COMPANY (US) 1977-12-06 US disclosed
US-3980479-A Positive-working immobile photographic compounds which cleave by intramolecular nucleophilic displacement in alkali unless oxidized EASTMAN KODAK COMPANY (US) 1976-09-14 US disclosed
US-3959223-A Oxidation-reduction diphenoquinone-diphenonhydroquinone polymers GENERAL ELECTRIC COMPANY (US) 1976-05-25 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 QDPR 3179/4885ACMSD 237/4885HDAC4 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.