SCHEMBL6881909

SCHEMBL6881909

O=C(OCC(COc1ccccc1)OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
PTPN1 P18031 2/20 0.53
SERPINE1 P05121 1/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
TSHR P16473 2/20 0.49
LMNA P02545 2/20 0.49
ALOX12 P18054 1/20 0.49
PRKCA P17252 1/20 0.49
MAPK1 P28482 2/20 0.48
GAA P10253 1/20 0.48
CYP19A1 P11511 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MAPT P10636 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
TP53 P04637 1/20 0.46
ADRB2 P07550 2/20 0.46
ADRB1 P08588 2/20 0.46
ADRB3 P13945 2/20 0.46
PTPN2 P17706 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tribenzoin SCHEMBL28609 0.90 ALDH1A1 (0.67) ALDH1A1PTPN1SERPINE1KMT2AMEN1
SCHEMBL6936775 0.88 TSHR (0.52) ALDH1A1KMT2AMEN1TSHRLMNA
SCHEMBL11957637 0.88 LMNA (0.50) ALDH1A1KMT2AMEN1TSHRLMNA
SCHEMBL6879080 0.87 ALDH1A1 (0.51) ALDH1A1PTPN1KMT2AMEN1TSHR
SCHEMBL13809716 0.86 SMN1; SMN2 (0.57) ALDH1A1PTPN1SERPINE1TSHRPRKCA
SCHEMBL13809706 0.86 SMN1; SMN2 (0.57) ALDH1A1PTPN1SERPINE1TSHRPRKCA
SCHEMBL13599580 0.85 ALDH1A1 (0.61) ALDH1A1PTPN1SERPINE1KMT2AMEN1
SCHEMBL13809721 0.84 SMN1; SMN2 (0.59) ALDH1A1PTPN1SERPINE1KMT2AMEN1
SCHEMBL13809707 0.84 ADRB2 (0.60) ALDH1A1PTPN1KMT2ALMNAGAA
SCHEMBL13809710 0.84 ADRB2 (0.60) ALDH1A1PTPN1KMT2ALMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040260039-A1 Process for producing organic compound epoxy resin composition, cured article obtained from the epoxy resin, and semiconductor device obtained with epoxy resin MITSUI CHEMICALS, INC. (JP) 2004-12-23 US disclosed
EP-0950649-B1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides MITSUI CHEMICALS INC (JP) 2003-03-26 EP disclosed
US-6130346-A ESTERIFICATION, CARBONATION, SULFONATION, ETHERIFICATION MITSUI CHEMICALS, INC. (JP) 2000-10-10 US disclosed
EP-0950649-A1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides Mitsui Chemicals, Inc. (JP) 1999-10-20 EP disclosed