Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885309 | 0.84 | P2RX7 (0.41) | P2RX7PPARGERCC1FEN1ERCC4 | |
| SCHEMBL6882914 | 0.82 | TACR1 (0.45) | ERCC1FEN1ERCC4 | |
| SCHEMBL6017784 | 0.73 | P2RX7 (0.45) | P2RX7EPHX2PPARGNTRK1ALOX5 | |
| SCHEMBL6882031 | 0.73 | SLC6A4 (0.36) | ERCC1FEN1ERCC4 | |
| SCHEMBL6884591 | 0.72 | ERCC1 (0.50) | PPARGERCC1FEN1ERCC4 | |
| SCHEMBL15560763 | 0.70 | EPHX2 (0.43) | P2RX7EPHX2PPARGNTRK1 | |
| SCHEMBL6651068 | 0.68 | ERCC1 (0.52) | ERCC1FEN1ERCC4 | |
| SCHEMBL18257284 | 0.67 | AR (0.46) | P2RX7EPHX2PPARGNTRK1ALOX5 | |
| SCHEMBL12641933 | 0.67 | HDAC3 (0.52) | P2RX7EPHX2PPARGHDAC3HDAC1 | |
| SCHEMBL6355022 | 0.67 | EPHX2 (0.53) | P2RX7EPHX2PPARGHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096128-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-11 | — | — | WO | claimed |