Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017819 | 0.87 | LMNA (0.48) | CNR2SMN1; SMN2MMP13ADORA2A | |
| SCHEMBL6651068 | 0.81 | ERCC1 (0.52) | ERCC1FEN1ERCC4EGLN1SMN1; SMN2 | |
| SCHEMBL6649380 | 0.78 | ERCC1 (0.54) | ERCC1FEN1ERCC4EGLN1SMN1; SMN2 | |
| SCHEMBL5645281 | 0.77 | ERCC1 (0.42) | ERCC1FEN1ERCC4TDP1ALDH1A1 | |
| SCHEMBL7156067 | 0.77 | ERCC1 (0.47) | ERCC1FEN1ERCC4KMT2AEGLN1 | |
| SCHEMBL6885131 | 0.76 | ERCC1 (0.46) | ERCC1FEN1ERCC4TDP1ALDH1A1 | |
| SCHEMBL6883227 | 0.76 | ERCC1 (0.47) | ERCC1FEN1ERCC4ALDH1A1MAPT | |
| SCHEMBL6885309 | 0.74 | P2RX7 (0.41) | ERCC1FEN1ERCC4MMP13PPARG | |
| SCHEMBL3534739 | 0.74 | ERCC1 (0.47) | ERCC1FEN1ERCC4SMN1; SMN2ADORA2A | |
| SCHEMBL6645591 | 0.74 | ERCC1 (0.47) | ERCC1FEN1ERCC4SMN1; SMN2TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096128-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-11 | — | — | WO | disclosed |