Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26679226 | 0.92 | POLB (0.59) | POLBSMN1; SMN2HTTHSD17B10KDM4E | |
| SCHEMBL13387961 | 0.84 | POLB (0.50) | POLBSMN1; SMN2HTTHSD17B10KDM4E | |
| SCHEMBL1399960 | 0.83 | HSD17B10 (0.63) | POLBSMN1; SMN2HTTHSD17B10KDM4E | |
| SCHEMBL13469239 | 0.83 | SMN1; SMN2 (0.57) | POLBSMN1; SMN2HSD17B10KDM4EALDH1A1 | |
| SCHEMBL25648716 | 0.82 | POLB (0.71) | POLBHTTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL21317665 | 0.82 | POLB (1.00) | POLBHSD17B10ALDH1A1HPGDFFAR1 | |
| SCHEMBL2723938 | 0.82 | POLB (0.77) | POLBFFAR1 | |
| SCHEMBL20232560 | 0.82 | POLB (0.71) | POLBHTTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL490637 | 0.82 | POLB (0.71) | POLBHTTHSD17B10ALDH1A1HPGD | |
| SCHEMBL8482547 | 0.81 | SMN1; SMN2 (0.56) | POLBSMN1; SMN2HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087655-A1 | 6-Substituted indanoyl amino acid conjugates as mimics to the biological activity of coronatine | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV (DE) | 2004-05-06 | — | — | US | disclosed |
| EP-1351922-A2 | 6-SUBSTITUTED INDANOYL AMINO ACID CONJUGATES AS MIMICS TO THE BIOLOGICAL ACTIVITY OF CORONATINE | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002055480-A2 | 6-SUBSTITUTED INDANOYL AMINO ACID CONJUGATES AS MIMICS TO THE BIOLOGICAL ACTIVITY OF CORONATINE | MAX PLANCK GESELLSCHAFT (DE) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087655-A1 | 6-Substituted indanoyl amino acid conjugates as mimics to the biological activity of coronatine | CORO1C, CORO1A, AGER | POLB 4155/4885SMN1; SMN2 4790/4885HTT 1965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.