Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16736898 | 0.85 | TRPA1 (0.48) | SMN1; SMN2HTTTP53HSP90AA1NUDT1 | |
| SCHEMBL2052453 | 0.79 | TRPA1 (0.52) | SMN1; SMN2LMNAHTTTP53NFKB1 | |
| SCHEMBL7076137 | 0.78 | ABL1 (0.43) | SMN1; SMN2NPC1RAB9ATP53APP | |
| SCHEMBL11877058 | 0.78 | NUDT1 (0.50) | SMN1; SMN2EPHX1EPHX2NPSR1NPC1 | |
| SCHEMBL8712858 | 0.75 | APP (0.37) | APPBACE1PTPN5RXRARXRB | |
| SCHEMBL20640289 | 0.73 | TRPA1 (0.42) | LMNAHSP90AA1NUDT1BACE1TYR | |
| SCHEMBL17878526 | 0.73 | APP (0.61) | LMNAHTTNFKB1APPTYR | |
| SCHEMBL918998 | 0.72 | GAA (0.49) | NPC1LMNAHTTRAB9ATP53 | |
| SCHEMBL9271805 | 0.72 | KDM4E (0.42) | SMN1; SMN2EPHX1EPHX2NPSR1NPC1 | |
| SCHEMBL6882613 | 0.72 | ALOX5 (0.55) | NPC1LMNAHTTRAB9AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753451-B2 | REACTING KETO COMPOUND, 1,3-DIOXOLANE, AND AN AMMONIUM HALIDE TO YIELD A B-AMINOKETONE; REACTING WITH N-ACETYLMETHYLPYRIDINIUM HALIDE; FRIEDEL-CRAFTS ALKYLATION | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-06-22 | — | — | US | disclosed |
| US-20030191349-A1 | Process for the preparation of phenylphenol compounds | CIBA SPECIALTY CHEMICALS CORP. | 2003-10-09 | — | — | US | disclosed |
| EP-1313689-A1 | PROCESS FOR THE PREPARATION OF PHENYLPHENOL COMPOUNDS | Ciba SC Holding AG (CH) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018311-A1 | PROCESS FOR THE PREPARATION OF PHENYLPHENOL COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-03-07 | — | — | WO | disclosed |
| US-5723500-A | WATER INSOLUBLE, NONCATIONIC, ANTIBACTERIAL, STERICALLY HINDERED PHENOL; MOUTHWASHES, DENTIFRICES | COLGATE-PALMOLIVE COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191349-A1 | Process for the preparation of phenylphenol compounds | PAH, CYP1A1, CYP2D6 | SMN1; SMN2 4876/4885EPHX1 1804/4885EPHX2 2372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.