Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA7 | P43166 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2648346 | 0.81 | ALDH1A1 (0.37) | POLBCYP1A2KDM4ELMNATSHR | |
| SCHEMBL2591834 | 0.75 | GABRA2 (0.43) | POLBCYP1A2KDM4ELMNAALDH1A1 | |
| SCHEMBL9732870 | 0.70 | CYP1A2 (0.40) | CYP1A2KDM4ELMNATSHRALDH1A1 | |
| SCHEMBL4773450 | 0.69 | CYP1A2 (0.39) | CYP1A2KDM4ELMNATSHRALDH1A1 | |
| SCHEMBL11259365 | 0.66 | CYP1A2 (0.42) | POLBCYP1A2KDM4ELMNATSHR | |
| SCHEMBL9626894 | 0.65 | TSHR (0.48) | CYP1A2KDM4ELMNATSHRALDH1A1 | |
| SCHEMBL10462143 | 0.65 | KDM4E (0.50) | POLBKDM4ELMNATSHRALDH1A1 | |
| SCHEMBL818614 | 0.63 | LMNA (0.43) | POLBCYP1A2KDM4ELMNATSHR | |
| SCHEMBL818456 | 0.63 | CA12 (0.44) | POLBCYP1A2KDM4ELMNATSHR | |
| SCHEMBL2649246 | 0.62 | ALDH1A1 (0.39) | POLBKDM4ELMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1373210-A1 | HETEROCYCLIC DIAMIDE INVERTEBRATE PEST CONTROL AGENTS | E. I. du Pont de Nemours and Company (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002070483-A1 | HETEROCYCLIC DIAMIDE INVERTEBRATE PEST CONTROL AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-09-12 | — | — | WO | disclosed |