Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 8/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.54 |
| ▸ | CSNK2A3 | Q8NEV1 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1324877 | 0.78 | PIM1 (0.44) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL4423923 | 0.76 | KMT2A (0.40) | KDM4EMAPTHPGDALDH1A1GAA | |
| SCHEMBL4427615 | 0.73 | CYP1A2 (0.44) | KDM4EMAPTHSD17B10L3MBTL1HPGD | |
| SCHEMBL3605347 | 0.70 | KDM4E (1.00) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL4927890 | 0.69 | NCOA1 (0.44) | KDM4EMAPTHSD17B10L3MBTL1HPGD | |
| Hydrochloric Acid SCHEMBL11652791 | 0.69 | KDM4E (0.97) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL4661897 | 0.68 | KDM4E (0.58) | KDM4EMAPTHSD17B10HPGDGLA | |
| SCHEMBL8440444 | 0.68 | CSNK2A1 (0.57) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL11830321 | 0.68 | CSNK2A1 (0.59) | PIM1CSNK2A1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL2398840 | 0.67 | AHR (0.52) | USP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004101767-A2 | CBI ANALOGUES OF THE DUOCARMYCINS AND CC-1065 | THE SCRIPPS RESEARCH INSTITUTE (US) | 2004-11-25 | — | — | WO | disclosed |