Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | GLA | P06280 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | CSNK2A1 | P68400 | 5/20 | 0.72 |
| ▸ | PIM1 | P11309 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.67 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.67 |
| ▸ | CSNK2A3 | Q8NEV1 | 4/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11652791 | 0.98 | KDM4E (0.97) | KDM4EHPGDMAPTGLATDP1 | |
| SCHEMBL10412026 | 0.86 | KDM4E (0.76) | KDM4EHPGDMAPTGLATDP1 | |
| SCHEMBL11110903 | 0.85 | KDM4E (0.74) | KDM4EHPGDMAPTGLATDP1 | |
| SCHEMBL16795594 | 0.85 | KDM4E (0.73) | KDM4EHPGDMAPTGLATDP1 | |
| SCHEMBL16271245 | 0.82 | KDM4E (1.00) | KDM4EHPGDMAPTGLATDP1 | |
| SCHEMBL2807607 | 0.79 | ALDH1A1 (1.00) | KDM4EHPGDMAPTGLATDP1 | |
| SCHEMBL23351596 | 0.77 | KDM4E (0.62) | KDM4EHPGDMAPTGLATDP1 | |
| SCHEMBL11111390 | 0.77 | KDM4E (0.62) | KDM4EHPGDMAPTGLATDP1 | |
| SCHEMBL16271258 | 0.77 | KDM4E (0.70) | KDM4EHPGDMAPTGLATDP1 | |
| SCHEMBL2895883 | 0.77 | HPGD (0.64) | KDM4EHPGDMAPTGLATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9643959-B2 | Tubulin polymerization inhibitor and method for synthesizing same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2017-05-09 | — | — | US | claimed |
| US-20160102078-A1 | NOVEL TUBULIN POLYMERIZATION INHIBITOR AND METHOD FOR SYNTHESIZING SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-04-14 | — | — | US | claimed |
| US-20250346575-A1 | ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2025-11-13 | — | — | US | disclosed |
| EP-4431505-A1 | ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF | Korea Research Institute of Chemical Technology (KR) | 2024-09-18 | — | — | EP | disclosed |
| WO-2023085785-A1 | ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF | 한국화학연구원 | 2023-05-19 | — | — | WO | disclosed |
| US-9643959-B2 | Tubulin polymerization inhibitor and method for synthesizing same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2017-05-09 | — | — | US | disclosed |
| US-9643959-B2 | Tubulin polymerization inhibitor and method for synthesizing same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2017-05-09 | — | — | US | disclosed |
| US-9643959-B2 | Tubulin polymerization inhibitor and method for synthesizing same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2017-05-09 | — | — | US | disclosed |
| US-20160102078-A1 | NOVEL TUBULIN POLYMERIZATION INHIBITOR AND METHOD FOR SYNTHESIZING SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-04-14 | — | — | US | disclosed |
| US-20160102078-A1 | NOVEL TUBULIN POLYMERIZATION INHIBITOR AND METHOD FOR SYNTHESIZING SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-04-14 | — | — | US | disclosed |
| US-20160102078-A1 | NOVEL TUBULIN POLYMERIZATION INHIBITOR AND METHOD FOR SYNTHESIZING SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2016-04-14 | — | — | US | disclosed |
| EP-1692124-B1 | BIARYL SULFONAMIDES AS MMP INHIBITORS | WYETH CORP (US) | 2008-10-15 | — | — | EP | disclosed |
| US-7420001-B2 | Biaryl sulfonamides and methods for using same | WYETH (US) | 2008-09-02 | — | — | US | disclosed |
| EP-1692124-A1 | BIARYL SULFONAMIDES AS MMP INHIBITORS | Wyeth (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005061477-A1 | BIARYL SULFONAMIDES AS MMP INHIBITORS | WYETH (US) | 2005-07-07 | — | — | WO | disclosed |
| US-20050143422-A1 | Biaryl sulfonamides and methods for using same | WYETH (US) | 2005-06-30 | — | — | US | disclosed |
| CN-1623537-A | Biaryl sulfonamides and its using method | WYETH CORP (US) | 2005-06-08 | — | — | CN | disclosed |
| US-4360679-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1982-11-23 | — | — | US | disclosed |
| US-4250317-A | OPTICAL BRIGHTENERS; FLUORESCENT DYES; TEXTILES; DETERGENTS | CIBA-GEIGY CORPORATION (US) | 1981-02-10 | — | — | US | disclosed |
| US-4146725-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160102078-A1 | NOVEL TUBULIN POLYMERIZATION INHIBITOR AND METHOD FOR SYNTHESIZING SAME | TUBB1, TUBB, TUBB6 | KDM4E 1749/4885HPGD 3658/4885MAPT 48/4885 |
| US-20050143422-A1 | Biaryl sulfonamides and methods for using same | STS, MMP3, AADAC | KDM4E 1421/4885HPGD 1110/4885MAPT 4416/4885 |
| US-20250346575-A1 | ISOINDOLINONE DERIVATIVE HAVING GLUTARIMIDE MOTHER NUCLEUS, AND USE THEREOF | CRBN, IDH1, IDH2 | KDM4E 2129/4885HPGD 1773/4885MAPT 1162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.