Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.46 |
| ▸ | SORD | Q00796 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30585414 | 0.82 | KDM4E (0.58) | HTTKDM4EGLAPARP1 | |
| SCHEMBL3112205 | 0.82 | HTT (0.58) | MAPTLMNAHSD17B10HTTKDM4E | |
| SCHEMBL9461754 | 0.81 | ALDH1A1 (0.56) | HSD17B10HTTKDM4EGLAPOLB | |
| SCHEMBL16432179 | 0.79 | ADRB1 (0.54) | KDM4EALDH1A1PARP1 | |
| SCHEMBL9461801 | 0.79 | PARP1 (0.43) | LMNAHSD17B10HTTKDM4EGLA | |
| SCHEMBL25294745 | 0.78 | KDM4E (0.63) | LMNAHSD17B10HTTKDM4EPOLB | |
| SCHEMBL30338644 | 0.78 | KDM4E (0.63) | LMNAHSD17B10HTTKDM4EPOLB | |
| SCHEMBL9461734 | 0.78 | DKK1 (0.50) | HSD17B10KDM4EALDH1A1TSHRGAA | |
| Hydrochloric Acid SCHEMBL30338561 | 0.77 | KDM4E (0.61) | LMNAHSD17B10HTTKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL25263828 | 0.77 | KDM4E (0.61) | LMNAHSD17B10HTTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004062613-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-07-29 | — | — | WO | disclosed |