SCHEMBL6883565

SCHEMBL6883565

CC(=O)C(NC(=O)NS(=O)(=O)c1ccc(C)cc1)NC(=O)NS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.57
LMNA P02545 3/20 0.55
KMT2A Q03164 1/20 0.54
ALDH1A1 P00352 5/20 0.52
TP53 P04637 2/20 0.52
TSHR P16473 2/20 0.52
KDM4E B2RXH2 2/20 0.52
NPSR1 Q6W5P4 1/20 0.52
ALB P02768 1/20 0.52
CYP2C9 P11712 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA13 Q8N1Q1 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19002605 0.83 GAA (0.63) GAALMNAKMT2AALDH1A1TP53
SCHEMBL9173395 0.83 GAA (0.63) GAALMNAKMT2AALDH1A1TP53
SCHEMBL5184740 0.82 LMNA (0.69) GAALMNAKMT2AALDH1A1TP53
SCHEMBL23467914 0.78 GAA (0.69) GAALMNAKMT2AALDH1A1TP53
SCHEMBL8712446 0.78 ALDH1A1 (0.67) GAALMNAKMT2AALDH1A1TP53
SCHEMBL4742655 0.78 LMNA (0.63) GAALMNAKMT2AALDH1A1TP53
SCHEMBL4536235 0.77 GAA (0.64) GAALMNAKMT2AKDM4ECA12
SCHEMBL6879344 0.77 GAA (0.64) GAALMNAKMT2AALDH1A1TP53
SCHEMBL19346088 0.77 GAA (0.60) GAALMNAKMT2AALDH1A1TP53
SCHEMBL5931251 0.77 SMN1; SMN2 (0.69) GAALMNAKMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed