Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.35 |
| ▸ | RELA | Q04206 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5097638 | 0.78 | MEN1 (0.48) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3139411 | 0.78 | NPC1 (0.42) | KMT2AMEN1NPC1RAB9ANFKB1 | |
| SCHEMBL908806 | 0.77 | NPC1 (0.46) | KMT2APOLBNOTUMMEN1NPC1 | |
| SCHEMBL4383111 | 0.74 | TP53 (0.46) | POLBNPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL12890439 | 0.74 | TDP1 (0.39) | KMT2APOLBMEN1NPC1RAB9A | |
| SCHEMBL5095475 | 0.71 | XDH (0.47) | KMT2APOLBMEN1NPC1RAB9A | |
| SCHEMBL23665406 | 0.68 | ALDH1A1 (0.54) | KMT2APOLBNOTUMMEN1NPC1 | |
| SCHEMBL11810896 | 0.68 | L3MBTL1 (0.52) | KMT2AMEN1NPC1RAB9ANFKB1 | |
| SCHEMBL6111135 | 0.68 | L3MBTL1 (0.52) | KMT2AMEN1NPC1RAB9ANFKB1 | |
| SCHEMBL738443 | 0.67 | CCR1 (0.46) | KMT2AMEN1NPC1RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6821992-B1 | ESPECIALLY AGAINST FUNGAL DISEASES OF PLANTS, E.G. MILDEWS AND PARTICULARLY CEREAL POWDERY MILDEW (ERYSIPHE GRAMINIS) AND VINE DOWNY MILDEW (PLASMOPARA VITICOLA), RICE BLAST (PYRICULARIA ORYZAE), ETC. | AVENTIS CROPSCIENCE S.A. (FR) | 2004-11-23 | — | — | US | disclosed |