Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 12/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563998 | 0.92 | MRGPRX4 (0.53) | MRGPRX4FFAR1FFAR4NR4A2MAOB | |
| SCHEMBL6888101 | 0.89 | MRGPRX4 (0.47) | NR1H2MRGPRX4FFAR1FFAR4SMPD1 | |
| SCHEMBL6882555 | 0.88 | MRGPRX4 (0.55) | NR1H2MRGPRX4FFAR1SMPD1NR4A2 | |
| SCHEMBL6885435 | 0.86 | MRGPRX4 (0.41) | MRGPRX4FFAR1MAOBMEN1KMT2A | |
| SCHEMBL6883847 | 0.86 | MRGPRX4 (0.47) | NR1H2MRGPRX4FFAR1SMPD1NR4A2 | |
| SCHEMBL6887724 | 0.83 | MRGPRX4 (0.53) | MRGPRX4SMPD1NR4A2MAOBSMN1; SMN2 | |
| SCHEMBL6564818 | 0.83 | MRGPRX4 (0.54) | MRGPRX4FFAR1FFAR4NR4A2 | |
| SCHEMBL6883961 | 0.82 | MRGPRX4 (0.55) | MRGPRX4SMPD1NR4A2MAOBSMN1; SMN2 | |
| SCHEMBL6889652 | 0.82 | RAB9A (0.52) | MRGPRX4KMT2ASMN1; SMN2 | |
| SCHEMBL6562981 | 0.82 | MRGPRX4 (0.52) | MRGPRX4SMPD1NR4A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |