Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775341 | 0.84 | LMNA (0.51) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL14621976 | 0.82 | CTSD (0.53) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL6951987 | 0.82 | CTSD (0.62) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL21163469 | 0.81 | LMNA (0.53) | LMNASTAT3NPC1RAB9ACTSD | |
| Iodide SCHEMBL10754021 | 0.81 | CTSD (0.61) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL4170685 | 0.79 | KMT2A (0.55) | RAB9ASMN1; SMN2GAAPOLB | |
| SCHEMBL8077219 | 0.79 | CTSD (0.53) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL13823241 | 0.78 | CTSD (0.49) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL3629922 | 0.78 | LMNA (0.46) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL5449981 | 0.78 | ATM (0.56) | LMNANPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096128-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-11-11 | — | — | WO | disclosed |