Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11702189 | 0.79 | CTSD (0.53) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL2775341 | 0.78 | LMNA (0.51) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL6883987 | 0.78 | LMNA (0.51) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL3632093 | 0.78 | LMNA (0.48) | LMNANPC1RAB9AL3MBTL1GAA | |
| SCHEMBL14621976 | 0.77 | CTSD (0.53) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL6951987 | 0.77 | CTSD (0.62) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL27607926 | 0.77 | CA1 (0.44) | LMNASTAT3NPC1RAB9ACTSD | |
| SCHEMBL5342931 | 0.77 | HPGD (0.38) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL16469273 | 0.75 | L3MBTL1 (0.46) | LMNASTAT3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21163469 | 0.75 | LMNA (0.53) | LMNASTAT3NPC1RAB9ACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142522-A1 | 1, 3-THIAZOL-2 (3H) -YLIDENE COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008121558-A1 | 1, 3-THIAZOL-2 (3H) -YLIDENE COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2008-10-09 | — | — | WO | disclosed |