Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6884147 | 1.00 | FDPS (0.43) | FDPSMAOBMAPTBACE1ALDH1A1 | |
| SCHEMBL6156205 | 0.88 | MAPT (0.42) | MAPTBACE1ALDH1A1ABCG2 | |
| SCHEMBL6156200 | 0.88 | MAPT (0.42) | MAPTBACE1ALDH1A1ABCG2 | |
| SCHEMBL6886676 | 0.83 | MAOB (0.49) | FDPSMAOBMAPTBACE1ALDH1A1 | |
| SCHEMBL6886681 | 0.83 | MAOB (0.49) | FDPSMAOBMAPTBACE1ALDH1A1 | |
| SCHEMBL6155870 | 0.74 | MEN1 (0.48) | MAPTALDH1A1 | |
| SCHEMBL6156382 | 0.69 | NR1H4 (0.44) | MAPTBACE1ALDH1A1ABCG2CYP3A4 | |
| SCHEMBL6156379 | 0.69 | NR1H4 (0.44) | MAPTBACE1ALDH1A1ABCG2CYP3A4 | |
| SCHEMBL14501336 | 0.69 | FDPS (0.73) | FDPSMAOBMAPTALDH1A1BCHE | |
| SCHEMBL14143303 | 0.69 | FDPS (0.73) | FDPSMAOBMAPTALDH1A1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |