Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | AKR1B10 | O60218 | 6/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886681 | 1.00 | MAOB (0.49) | MAOBCA12CA1CA2CA7 | |
| SCHEMBL6156379 | 0.86 | NR1H4 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6156382 | 0.86 | NR1H4 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6884147 | 0.83 | FDPS (0.43) | MAOBFDPSBACE1ALDH1A1MAPT | |
| SCHEMBL6884145 | 0.83 | FDPS (0.43) | MAOBFDPSBACE1ALDH1A1MAPT | |
| SCHEMBL6155464 | 0.76 | VDR (0.40) | MAOBNR1H4BACE1APPCHRNA7 | |
| SCHEMBL6155472 | 0.76 | VDR (0.40) | MAOBNR1H4BACE1APPCHRNA7 | |
| SCHEMBL6155469 | 0.76 | VDR (0.40) | MAOBNR1H4BACE1APPCHRNA7 | |
| SCHEMBL1434800 | 0.74 | CA12 (0.49) | MAOBCA12CA1CA2CA7 | |
| SCHEMBL14143629 | 0.74 | BACE1 (0.69) | MAOBCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |