Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689953 | 0.96 | GPR119 (0.32) | GPR119 | |
| SCHEMBL688431 | 0.81 | HPGD (0.50) | HPGDGPR119KDM4EPKM | |
| SCHEMBL1133757 | 0.78 | NR1H2 (0.43) | HPGDGPR119KDM4EPKM | |
| SCHEMBL689952 | 0.77 | HPGD (0.50) | HPGDGPR119KDM4EPKM | |
| SCHEMBL5258386 | 0.77 | NCF1 (0.40) | HPGDGPR119KDM4EPKM | |
| SCHEMBL6974684 | 0.77 | NR1H2 (0.36) | HPGDGPR119KDM4EPKM | |
| SCHEMBL1060376 | 0.76 | HPGD (0.45) | HPGDGPR119KDM4EPKM | |
| SCHEMBL3645886 | 0.74 | KDM4E (0.32) | HPGDGPR119KDM4EPKM | |
| SCHEMBL212033 | 0.73 | CHRM2 (0.42) | HPGDGPR119KDM4E | |
| SCHEMBL25405313 | 0.72 | MEN1 (0.49) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331506-B1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2013-07-03 | — | — | EP | disclosed |
| EP-2323980-B1 | 7-(PIPERAZINE-1-YMETHYL)-1H-INDOLE-2-CARBOXYLIC ACID (PHENYL)-AMIDE DERIVATIVES AND ALLIED COMPOUNDS AS P38 MAP KINASE INHIBITORS FOR THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INT (DE) | 2012-02-29 | — | — | EP | disclosed |
| EP-2331506-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010026095-A1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | WO | disclosed |