Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157330 | 0.82 | VDR (0.50) | LMNA | |
| SCHEMBL6884477 | 0.79 | KMT2A (0.55) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6885032 | 0.77 | KMT2A (0.46) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4169798 | 0.77 | VDR (0.40) | KMT2AMEN1MAPT | |
| SCHEMBL4169791 | 0.77 | VDR (0.40) | KMT2AMEN1MAPT | |
| SCHEMBL11108977 | 0.76 | KMT2A (0.53) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11735992 | 0.75 | HPGD (0.59) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30839637 | 0.73 | PPARA (0.52) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11115690 | 0.73 | KMT2A (0.61) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8285571 | 0.72 | KMT2A (0.59) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |