Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 9/20 | 0.44 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3280099 | 0.86 | VDR (0.53) | VDRCYP4F2CYP4A11 | |
| SCHEMBL6884474 | 0.82 | KMT2A (0.52) | LMNA | |
| SCHEMBL12235066 | 0.81 | CYP4F2 (0.67) | CYP4F2CYP4A11MAOBIL4I1LMNA | |
| SCHEMBL9660695 | 0.81 | MAOB (0.58) | CYP4F2CYP4A11MAOBIL4I1LMNA | |
| SCHEMBL1481937 | 0.81 | PRSS1 (0.55) | PKMCYP4F2CYP4A11MAOBIL4I1 | |
| SCHEMBL6155391 | 0.80 | MAOB (0.62) | PKMMAOBMAOA | |
| SCHEMBL18073734 | 0.79 | PKM (0.71) | PKMLMNA | |
| SCHEMBL6756665 | 0.78 | VDR (0.47) | VDR | |
| SCHEMBL18095253 | 0.78 | CYP4A11 (0.65) | CYP4F2CYP4A11MAOBIL4I1LMNA | |
| SCHEMBL4958280 | 0.78 | KAT6A (0.51) | CYP4F2CYP4A11MAOBIL4I1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |