Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CD38 | P28907 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PPP1R15A | O75807 | 1/20 | 0.41 |
| ▸ | MELK | Q14680 | 1/20 | 0.41 |
| ▸ | PPP1R15B | Q5SWA1 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17548952 | 1.00 | ALOX12 (0.55) | ALOX12HPGDGAARAB9APOLB | |
| SCHEMBL7602955 | 1.00 | ALOX12 (0.55) | ALOX12HPGDGAARAB9APOLB | |
| SCHEMBL3697881 | 0.82 | GAA (0.44) | ALOX12HPGDGAARAB9APOLB | |
| SCHEMBL534017 | 0.81 | L3MBTL1 (0.59) | ALOX12HPGDGAARAB9AMAPT | |
| SCHEMBL32680261 | 0.81 | L3MBTL1 (0.59) | ALOX12HPGDGAARAB9AMAPT | |
| SCHEMBL534016 | 0.81 | L3MBTL1 (0.59) | ALOX12HPGDGAARAB9AMAPT | |
| SCHEMBL2161103 | 0.81 | L3MBTL1 (0.59) | ALOX12HPGDGAARAB9AMAPT | |
| SCHEMBL1776974 | 0.80 | GRIN2D (0.57) | HPGDRAB9AMAPTLMNAHTT | |
| SCHEMBL534275 | 0.80 | GRIN2D (0.57) | HPGDRAB9AMAPTLMNAHTT | |
| SCHEMBL534274 | 0.80 | GRIN2D (0.57) | HPGDRAB9AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |
| EP-0950921-B1 | Thermally processable photosensitive material, image forming method and antifoggant | KONISHIROKU PHOTO IND (JP) | 2002-12-11 | — | — | EP | disclosed |