SCHEMBL32680261

SCHEMBL32680261

ON=Cc1cccc(Cl)c1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.59
PPP1R15A O75807 1/20 0.59
MELK Q14680 1/20 0.59
PPP1R15B Q5SWA1 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.49
ALDH1A1 P00352 4/20 0.47
LMNA P02545 3/20 0.47
KMT2A Q03164 3/20 0.47
HPGD P15428 2/20 0.47
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
HTT P42858 1/20 0.43
TSHR P16473 1/20 0.43
ALOX12 P18054 1/20 0.43
MAPT P10636 4/20 0.42
MEN1 O00255 2/20 0.40
FAAH O00519 1/20 0.40
MGLL Q99685 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2161103 1.00 L3MBTL1 (0.59) L3MBTL1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL534017 1.00 L3MBTL1 (0.59) L3MBTL1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL534016 1.00 L3MBTL1 (0.59) L3MBTL1PPP1R15AMELKPPP1R15BNPSR1
Bicarbonate SCHEMBL11884724 0.92 ALDH1A1 (0.54) L3MBTL1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL534274 0.82 GRIN2D (0.57) L3MBTL1NPSR1ALDH1A1LMNAKMT2A
SCHEMBL30862631 0.82 GRIN2D (0.57) L3MBTL1NPSR1ALDH1A1LMNAKMT2A
SCHEMBL1776974 0.82 GRIN2D (0.57) L3MBTL1NPSR1ALDH1A1LMNAKMT2A
SCHEMBL534275 0.82 GRIN2D (0.57) L3MBTL1NPSR1ALDH1A1LMNAKMT2A
SCHEMBL6884832 0.81 ALOX12 (0.55) L3MBTL1PPP1R15AMELKPPP1R15BNPSR1
SCHEMBL7602955 0.81 ALOX12 (0.55) L3MBTL1PPP1R15AMELKPPP1R15BNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702017-A1 SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd (KY) 2026-03-04 EP disclosed