Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | IAPP | P10997 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4843534 | 0.82 | CA12 (0.47) | GABRA1GABRB2ALDH1A1GAAMAPT | |
| SCHEMBL1955296 | 0.79 | IDO1 (0.51) | IDO1ALDH1A1GAAMAPT | |
| SCHEMBL11413705 | 0.79 | GABRA1 (0.52) | GABRA1GABRB2ALDH1A1GAAMAPT | |
| SCHEMBL20810767 | 0.78 | IDO1 (0.42) | IDO1ALDH1A1GAAMAPTTSHR | |
| SCHEMBL5839292 | 0.78 | SCN5A (0.48) | GABRA1GABRB2ALDH1A1GAAMAPT | |
| SCHEMBL28626455 | 0.77 | ALDH1A1 (0.50) | GABRA1GABRB2IDO1ALDH1A1PKM | |
| SCHEMBL29400968 | 0.76 | HPGD (0.43) | IDO1ALDH1A1TSHRCYP2C19HIF1A | |
| SCHEMBL7773989 | 0.75 | BID (0.47) | ALDH1A1MAPTTSHRBIDMCL1 | |
| SCHEMBL29113974 | 0.75 | GABRA1 (0.46) | GABRA1GABRB2ALDH1A1GAAMAPT | |
| SCHEMBL5839192 | 0.74 | KCNH2 (0.46) | GABRA1GABRB2ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1442009-A1 | PRODUCTION OF KETO ACIDS | Ciba SC Holding AG (CH) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037846-A1 | PRODUCTION OF KETO ACIDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-08 | — | — | WO | disclosed |